Thanks peterB
Yes, you are correct
Our end users are using a physical zero client (Wyse P25) that has the View Client built in. The USB receipt printer is physically plugged into the zero client. The software for the printer configures it to use COM2. We are using Windows 7 Pro and the software is install on the VDI client OS.
I have call into the printer support group to see if their configuration can use another COM port, but I am thinking the answer is no.