1) I was able to successfully change the COM2 settings in Device Manager to be listed as COM64 and not COM2. This allowed my printer software use the "available" COM2. However, when I try to print I receive a generic error message "Device is not connected". So I am not sure if this is a COM port related issue or an issue with the physical printer plugged into the zero client and not playing nice with View
2) If I disable the serial ports in the guest BIOS, it does not list them in the guest OS Windows Device Manager but the printer software still has COM1 and COM2 in use.